ESR9

Expanding ciliary pathways and ontologies


Current public knowledge of ciliary function, including ciliary transport, ciliogenesis and signalling, remains woefully underrepresented in public databases (e.g. Reactome). There is also a need to put the mechanisms described by partners into a complete context in order that the results can be exploited and understood fully. The aim of ESR9 is thus to expand the current set of cilia-relevant pathways based both on prior findings and those uncovered by partners. These will be generated in concert with partners at meetings and secondments. The project will also involve careful interrogation of gene/protein components to help identify molecular mechanisms for ciliary interactions and complexes.

Partner: Cell Networks Gmbh, Heidelberg, Germany

Supervisor: dr G. Apic